有關 維他命C 的研究
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Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer*
Ascorbic acid metabolism is associated with a number of mechanisms known to be involved in host resistance to malignant disease. Cancer patients are significantly depleted of ascorbic acid, and in our opinion this demonstrable biochemical characteristic indicates a substantially increased requirement and utilization of this substance to potentiate these various host resistance factors.
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.
Human pharmacokinetics data indicate that i.v. ascorbic acid(ascorbate) in pharmacologic concentrations could have an unan-ticipated role in cancer treatment.
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
These data support the testing of pharmacologic ascorbate in adjunctive treatments for cancers prone to high failure rates with conventional therapeutic regimens, such as pancreatic cancer
Effect of high dose intravenous ascorbic acid on the level of inflammation in patients with rheumatoid arthritis
Our data suggest that IVC therapy with dosages of 7.5 g - 50 g can reduce inflammation. The level of inflammation as measured by C-reactive protein levels was decreased on average by 44%. Based on our pilot study, we hypothesize that IVC therapy can be a useful strategy in treating RA.
Intravenously administered vitamin C as cancer therapy: three cases
Using the National Cancer Institute Best Case Series guidelines, the authors reviewed 3 cases of advanced cancer where patients had unexpectedly long survival times after receiving high-dose intravenous vitamin C therapy
High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer
n this review, we provide an elaborate overview of pre-clinical and clinical studies using high-dose IVC as anti-cancer agent, as well as a detailed evaluation of the main known molecular mechanisms involved. A special focus is put on global molecular profiling studies in this respect. In addition, an outlook on future implications of high-dose vitamin C in cancer treatment is presented and recommendations for further research are discussed.
Effect of High-dose Vitamin C Combined With Anti-cancer Treatment on Breast Cancer Cells
This study attempted to demonstrate the in vitro anti-cancer activity of high-dose vitamin C in combination with conventional treatment in breast cancer.